Alternative medicine for chemotherapy and radiotherapy

According to a research report published in the journal Nature Medicine, a new experimental antibody drug has opened up a new direction for people who need stem cell transplants (found in bone marrow) to treat blood cancers.

Dr. Agnieszka Czechowicz, MD. Photo: STANFORD

The study found that the antibody-based drug, briquilimab, did not cause the toxicity or side effects of chemotherapy and radiation. Briquilimab targets CD117, a protein found on blood stem cells that controls their growth. The trial was conducted at Stanford Medical School (California, USA) on three children with Fanconi anemia, a rare genetic disorder that can cause cancer. Each child received just one infusion of briquilimab 12 days before the stem cell transplant. The results showed that after 30 days, healthy cells from the donor had almost completely covered the children's bone marrow.

The team is now conducting mid-stage trials with more children with Fanconi anemia, and plans to test the treatment in other genetic diseases that require bone marrow transplants. Not only does this approach eliminate the need for radiation and chemotherapy, but it also has superior results, said study co-lead author Agnieszka Czechowicz, MD, PhD.

KHANH MINH

Source: https://www.sggp.org.vn/thuoc-thay-hoa-tri-va-xa-tri-post810910.html